Internal Medicine
Aficamten Shows Major Promise for Nonobstructive HCM
Discover how aficamten improves exercise capacity and quality of life in nonobstructive hypertrophic cardiomyopathy based on ACACIA-HCM trial findings.
Can Tailored Antibiotics Shorten Endocarditis Therapy?
The POET-II trial reveals that response-tailored antibiotic therapy safely shortens infective endocarditis treatment duration in clinically stable adults.
AI-ECG System Detects Transthyretin Amyloid Cardiomyopathy
Discover how deep learning AI applied to routine ECGs enables rapid transthyretin amyloid cardiomyopathy screening and prioritizes advanced imaging.
2025 Adult Obesity Guidelines: Modern Care & GLP-1 Use
Discover the 2025 adult obesity management guideline updates, featuring revised screening cutoffs, GLP-1 therapies, and long-term treatment strategies.
Modern Adult Obesity Management: New VA/DoD Guidelines
Discover the updated 2025 VA/DoD clinical guidelines for adult obesity management, highlighting flexible pharmacotherapy and comprehensive lifestyle care.
Daily Zinc Cuts Infection Risk in Pediatric Sickle Cell
Explore findings from the ZIPS-2 trial showing daily zinc supplementation reduces infection rates in young children with sickle cell anemia.
STArT Trial: Does IV Arginine Shorten Sickle Cell Pain?
STArT trial finds IV arginine does not reduce time to crisis resolution or opioid use in pediatric sickle cell disease acute pain episodes. Read key findings.
Targeted Therapies in Myeloproliferative Neoplasms
Explore the genetic drivers, clonal evolution, and targeted therapies in myeloproliferative neoplasms to optimize long-term patient outcomes.
Randomized QI Trials: A Novel Ethical Oversight Guide
Explore how randomized quality improvement trials optimize healthcare delivery through ethical oversight, practical randomization, and active monitoring.
How Tracking Heart Stress Predicts Longevity and CVD Risk
Discover how longitudinal NT-proBNP heart stress assessment improves risk prediction for cardiovascular disease and mortality in older adults.
Evidence-Based Tobacco Cessation Strategies for LMICs
Explore evidence-based tobacco cessation strategies in LMICs like India, combining MPOWER, Ask-Advise-Connect models, NRT, and digital support.
Perioperative Cardiovascular Risk in Noncardiac Surgery
Learn key strategies to manage perioperative cardiovascular risk in patients undergoing noncardiac surgery based on the latest 2024 AHA/ACC guidelines.
Surgical Fusion vs Watchful Waiting in Hallux Rigidus
A randomized trial proves first MTPJ arthrodesis significantly reduces walking pain in severe hallux rigidus compared to watchful waiting at 12 months.
Comprehensive IBD Health Maintenance in Primary Practice
Discover essential IBD health maintenance strategies, including vaccinations, cancer screening, bone health, and collaborative primary care management.
DOACs vs Warfarin in Atrial Fibrillation Mitral Stenosis
A recent study evaluates DOACs versus warfarin in atrial fibrillation and mitral stenosis, showing higher stroke risk but lower MI risk with DOACs.
Asundexian Redefines Secondary Ischemic Stroke Prevention
Asundexian stroke prevention reduces recurrent ischemic stroke risk without increasing major bleeding risk when added to antiplatelet therapy after TIA.
How Blood Pressure-Lowering Drugs Protect Heart in CKD
A major study confirms that blood pressure-lowering drugs reduce major cardiovascular events across all stages of chronic kidney disease regardless of G category.
Sacubitril vs Dapagliflozin: HF Health Status at 6 Months
A randomized trial comparing sacubitril-valsartan vs dapagliflozin and torsemide vs furosemide showed no difference in HF health status at six months.
Whole Health Teams Outperform CBT for Chronic Pain Care
A 12-month study shows whole health team care reduces pain interference more than CBT or usual care in veterans with chronic pain management needs.
EVT Improves Outcomes in Large-Core Ischemic Stroke
Recent clinical evidence shows endovascular thrombectomy improves 90-day functional outcomes and survival in large core ischemic stroke within 24 hours.
Asundexian Prevents Recurrent Stroke Without Bleeding
Discover how asundexian stroke prevention reduces recurrent ischemic stroke by 26% without increasing major bleeding risk in acute noncardioembolic TIA.
Why CKD Blood Pressure Control Is Crucial for Heart Health
Lowering blood pressure reduces major cardiovascular risk across all CKD stages. Explore new clinical findings on cardiorenal protection for your patients.
Symptomatic Heart Failure: Comparing 6-Month Outcomes
A study compares sacubitril-valsartan, dapagliflozin, torsemide, and furosemide for 6-month health status outcomes in symptomatic heart failure.
Why Whole Health Teams Outperform CBT in Chronic Pain Care
Discover how a whole health team approach improves chronic pain management more effectively than CBT or usual medical care.
EVT vs Medical Therapy in Large-Core Ischemic Stroke
Endovascular thrombectomy within 24 hours improves functional outcomes and reduces 90-day mortality in large-core ischemic stroke vs medical care.
Doravirine Regimen Reduces Weight Gain in Initial HIV Care
The Opti-DOR trial shows doravirine-based HIV therapy limits treatment-associated weight gain while maintaining high viral suppression in adult patients.
Dapagliflozin Prevents Kidney Injury in Heart Surgery
A trial evaluated if dapagliflozin acute kidney injury reduction occurs in elective cardiac surgery. Discover key clinical outcomes and study insights.
How New US State Laws Transform IMG Medical Licensing
US states are enacting historic laws to streamline IMG medical licensing, removing mandatory domestic residency requirements for foreign-trained doctors.
New US Licensing Pathways for Foreign-Trained Physicians
Learn how new state laws transform international medical graduate licensure in the United States and streamline career options.
Perioperative Enfortumab Vedotin-Pembrolizumab in MIBC
Phase 3 trial shows perioperative enfortumab vedotin-pembrolizumab improves event-free and overall survival in cisplatin-eligible bladder cancer patients.
Why Home Dialysis Fails to Reach Patients Who Need It Most
Explore the history of home dialysis barriers, political struggles, and socio-economic hurdles, with lessons for expanding dialysis access in India.
How to Master the New STROBE EPIC Reporting Standard
Discover how the new STROBE EPIC guideline changes reporting observational studies for incidence and prevalence, improving clinical research quality.
Olorofim: A Game-Changer for Intractable Fungal Infections
Discover how the novel antifungal olorofim offers a powerful new option for treating refractory and disseminated coccidioidomycosis in clinical trials.
Andes Virus Infection: Guidelines for Indian Doctors
Learn about Andes virus infection, its transmission, and expert clinical management guidelines tailored for healthcare providers and Indian clinicians.
Is Indefinite Myeloma Maintenance Therapy Finally Dead?
The ENDURANCE trial shows that fixed-duration lenalidomide maintenance therapy has equal survival benefits to indefinite therapy with much lower toxicity.
Extended DAPT Prevents Heart Attacks in Multivessel CAD
Explore why extended dual antiplatelet therapy after DES implantation protects patients with multivessel CAD from heart attacks without increasing bleeding.
Are Healthcare-Associated Infections Falling in Hospitals?
Explore the latest NEJM study on healthcare-associated infections. Discover how infection rates declined from 2015 to 2023 and what it means for doctors.
Effective Fibromyalgia Management in Modern Primary Care
Explore modern fibromyalgia management strategies. Learn how central nervous system hyperresponsiveness is targeted to achieve clinical homeostasis.
GLP-1s and Optic Neuropathy: New Data Clarifies Risk
Discover the actual ischemic optic neuropathy risk with GLP-1 receptor agonists in this new nationwide cohort study comparing GLP-1s to SGLT-2 inhibitors.
Do GLP-1 RAs Truly Help Patients Stop Basal Insulin?
Explore why adding GLP-1 RAs to basal insulin does not improve rates of insulin discontinuation in type 2 diabetes compared to oral diabetes therapies.
Tighter Dietary Supplement Rules: ACP Calls for Action
Discover the ACP’s new policy recommendations to improve dietary supplements safety and how these reforms impact clinical practice in India and globally.
Do GLP-1 Agonists Raise Ischemic Optic Neuropathy Risk?
This target trial emulation explores the link between GLP-1 receptor agonists and ischemic optic neuropathy risk in type 2 diabetes patients.
Do GLP-1 Receptor Agonists Cause Sudden Vision Loss?
A nationwide cohort study evaluates the risk of NAION associated with GLP-1 receptor agonists compared to SGLT-2 inhibitors in type 2 diabetes.
Do GLP-1s Really Help Type 2 Diabetes Patients Stop Insulin?
A target trial emulation reveals that GLP-1 receptor agonists do not increase insulin discontinuation rates compared to oral diabetes therapies.
Is Your Patient’s Supplement Safe? ACP Demands Reform
The ACP calls for stricter dietary supplement regulation to protect public health. Learn how these updates affect safety standards and patient care.
Are GLP-1 Receptor Agonists Harming Patient Vision?
This target trial emulation explores whether GLP-1 receptor agonists increase the risk of ischemic optic neuropathy in patients with type 2 diabetes.
YEARS Algorithm Safely Spares CTPA in Cancer Patients
Learn how the YEARS algorithm in cancer safely reduces the need for CTPA imaging by twenty-two percent in patients with suspected pulmonary embolism.
How Amyloid Clearance Halts Alzheimer’s Brain Decay
This clinicopathologic case report analyzes how amyloid clearance from anti-amyloid therapies reduces downstream tau pathology in Alzheimer disease.
Is Aspirin Alone Enough After Hip or Knee Arthroplasty?
Learn why aspirin alone is safe and effective for postoperative thromboprophylaxis after total hip or knee replacement, according to the EPCAT III study.
Is Left Atrial Appendage Closure Safe for High-Risk AF?
A recent study shows left atrial appendage closure is not noninferior to medical therapy for patients with atrial fibrillation at high risk of stroke.