Internal Medicine
LAIS Trial: Can Loberamisal Transform Stroke Recovery?
Explore findings from the LAIS trial on loberamisal in acute stroke, showing enhanced 90-day functional recovery and safety within 48 hours of onset.
Severe Methemoglobinemia Outbreak: Fuel Toxicity Alert
Learn about severe methemoglobinemia caused by fuel additives, key diagnostic signs, methylene blue dosing, and risks of delayed hemolytic anemia.
Modern Multiple Myeloma Care: Trials to Clinical Practice
Explore modern multiple myeloma treatment strategies, from quadruplet induction and stem cell transplant to CAR T-cell sequencing and MRD testing.
Tuberculosis Today: A Step-by-Step Practical Care Guide
Explore evidence-based tuberculosis diagnosis and treatment guidelines, screening strategies, molecular assays, and therapeutic regimens for clinical care.
Optimal Hemoglobin Levels: Is Borderline Normal Safe?
A prospective UK Biobank study links blood hemoglobin concentration to mortality risk, revealing surprising risks in borderline normal clinical ranges.
Improving Discharge Transitions in Alcohol Use Disorder
A systematic review assesses hospital-based strategies to improve outpatient alcohol use disorder follow-up, revealing promising multi-component models.
Can Tozorakimab Prevent Persistent COPD Exacerbations?
Phase 3 OBERON and TITANIA trials show tozorakimab reduces COPD exacerbations across smoking statuses and eosinophil counts.
Mastering Tuberculosis Care: Modern Diagnostic Pathways
Explore modern tuberculosis management, rapid molecular diagnostics, and evidence-based treatment regimens to optimize outcomes in high-burden settings.
Borderline Hemoglobin Levels and Mortality: New Evidence
Discover new data on hemoglobin concentration and mortality. See why borderline anemia and elevated hemoglobin increase long-term mortality risk.
Can Inpatient Strategies Boost Alcohol Care Linkage?
Hospital discharge interventions for alcohol use disorder improve outpatient linkage when combining medications, behavioral care, and coordination.
Navigating Pulmonary Nodules: Evidence-Based Management
Master pulmonary nodule management with evidence-based guidance. Learn how to assess malignancy risk, monitor stability, and select biopsies.
NOAC vs ASA: Breakthrough Findings in Post-TAVI Care
Explore the ACASA-TAVI trial findings comparing NOAC and ASA monotherapy for leaflet thrombosis prevention and long-term safety after TAVI.
REVEAL Study: Accurate Diagnosis of Cardiac Amyloidosis
The REVEAL trial demonstrates high sensitivity and specificity for cardiac amyloidosis PET CT imaging using 124I-evuzamitide in suspected heart disease.
Gene Silencer Therapy Cuts Mortality in ATTR-CM Patients
Discover new phase 3 meta-analysis insights on gene silencer therapy for ATTR-CM, highlighting mortality reduction and combination treatment effects.
Low-Voltage Zone Ablation for Persistent AF: Trial Data
Explore the IDEAL-AF trial findings on low-voltage zone ablation for persistent atrial fibrillation to improve rhythm control and clinical outcomes.
Does Evolocumab Before PCI Improve Acute MI Outcomes?
Administering evolocumab before PCI rapidly lowers LDL-C levels in acute MI patients, according to new 1-year findings from the AMUNDSEN clinical trial.
Does Posterior Wall Isolation Improve PFA in Persistent AF?
The PIFPAF-PFA trial evaluated whether adding posterior wall isolation to pulsed field ablation improves persistent AF outcomes.
Can Digital Outreach Strategies Improve Statin Adherence?
Discover how adaptive digital outreach improves statin adherence in high-risk ASCVD patients, based on findings from the ADHERE-ASCVD randomized clinical trial.
Aficamten Shows Major Promise for Nonobstructive HCM
Discover how aficamten improves exercise capacity and quality of life in nonobstructive hypertrophic cardiomyopathy based on ACACIA-HCM trial findings.
Can Tailored Antibiotics Shorten Endocarditis Therapy?
The POET-II trial reveals that response-tailored antibiotic therapy safely shortens infective endocarditis treatment duration in clinically stable adults.
AI-ECG System Detects Transthyretin Amyloid Cardiomyopathy
Discover how deep learning AI applied to routine ECGs enables rapid transthyretin amyloid cardiomyopathy screening and prioritizes advanced imaging.
2025 Adult Obesity Guidelines: Modern Care & GLP-1 Use
Discover the 2025 adult obesity management guideline updates, featuring revised screening cutoffs, GLP-1 therapies, and long-term treatment strategies.
Modern Adult Obesity Management: New VA/DoD Guidelines
Discover the updated 2025 VA/DoD clinical guidelines for adult obesity management, highlighting flexible pharmacotherapy and comprehensive lifestyle care.
Daily Zinc Cuts Infection Risk in Pediatric Sickle Cell
Explore findings from the ZIPS-2 trial showing daily zinc supplementation reduces infection rates in young children with sickle cell anemia.
STArT Trial: Does IV Arginine Shorten Sickle Cell Pain?
STArT trial finds IV arginine does not reduce time to crisis resolution or opioid use in pediatric sickle cell disease acute pain episodes. Read key findings.
Targeted Therapies in Myeloproliferative Neoplasms
Explore the genetic drivers, clonal evolution, and targeted therapies in myeloproliferative neoplasms to optimize long-term patient outcomes.
Randomized QI Trials: A Novel Ethical Oversight Guide
Explore how randomized quality improvement trials optimize healthcare delivery through ethical oversight, practical randomization, and active monitoring.
How Tracking Heart Stress Predicts Longevity and CVD Risk
Discover how longitudinal NT-proBNP heart stress assessment improves risk prediction for cardiovascular disease and mortality in older adults.
Evidence-Based Tobacco Cessation Strategies for LMICs
Explore evidence-based tobacco cessation strategies in LMICs like India, combining MPOWER, Ask-Advise-Connect models, NRT, and digital support.
Perioperative Cardiovascular Risk in Noncardiac Surgery
Learn key strategies to manage perioperative cardiovascular risk in patients undergoing noncardiac surgery based on the latest 2024 AHA/ACC guidelines.
Surgical Fusion vs Watchful Waiting in Hallux Rigidus
A randomized trial proves first MTPJ arthrodesis significantly reduces walking pain in severe hallux rigidus compared to watchful waiting at 12 months.
Comprehensive IBD Health Maintenance in Primary Practice
Discover essential IBD health maintenance strategies, including vaccinations, cancer screening, bone health, and collaborative primary care management.
DOACs vs Warfarin in Atrial Fibrillation Mitral Stenosis
A recent study evaluates DOACs versus warfarin in atrial fibrillation and mitral stenosis, showing higher stroke risk but lower MI risk with DOACs.
Asundexian Redefines Secondary Ischemic Stroke Prevention
Asundexian stroke prevention reduces recurrent ischemic stroke risk without increasing major bleeding risk when added to antiplatelet therapy after TIA.
How Blood Pressure-Lowering Drugs Protect Heart in CKD
A major study confirms that blood pressure-lowering drugs reduce major cardiovascular events across all stages of chronic kidney disease regardless of G category.
Sacubitril vs Dapagliflozin: HF Health Status at 6 Months
A randomized trial comparing sacubitril-valsartan vs dapagliflozin and torsemide vs furosemide showed no difference in HF health status at six months.
Whole Health Teams Outperform CBT for Chronic Pain Care
A 12-month study shows whole health team care reduces pain interference more than CBT or usual care in veterans with chronic pain management needs.
EVT Improves Outcomes in Large-Core Ischemic Stroke
Recent clinical evidence shows endovascular thrombectomy improves 90-day functional outcomes and survival in large core ischemic stroke within 24 hours.
Asundexian Prevents Recurrent Stroke Without Bleeding
Discover how asundexian stroke prevention reduces recurrent ischemic stroke by 26% without increasing major bleeding risk in acute noncardioembolic TIA.
Why CKD Blood Pressure Control Is Crucial for Heart Health
Lowering blood pressure reduces major cardiovascular risk across all CKD stages. Explore new clinical findings on cardiorenal protection for your patients.
Symptomatic Heart Failure: Comparing 6-Month Outcomes
A study compares sacubitril-valsartan, dapagliflozin, torsemide, and furosemide for 6-month health status outcomes in symptomatic heart failure.
Why Whole Health Teams Outperform CBT in Chronic Pain Care
Discover how a whole health team approach improves chronic pain management more effectively than CBT or usual medical care.
EVT vs Medical Therapy in Large-Core Ischemic Stroke
Endovascular thrombectomy within 24 hours improves functional outcomes and reduces 90-day mortality in large-core ischemic stroke vs medical care.
Doravirine Regimen Reduces Weight Gain in Initial HIV Care
The Opti-DOR trial shows doravirine-based HIV therapy limits treatment-associated weight gain while maintaining high viral suppression in adult patients.
Dapagliflozin Prevents Kidney Injury in Heart Surgery
A trial evaluated if dapagliflozin acute kidney injury reduction occurs in elective cardiac surgery. Discover key clinical outcomes and study insights.
How New US State Laws Transform IMG Medical Licensing
US states are enacting historic laws to streamline IMG medical licensing, removing mandatory domestic residency requirements for foreign-trained doctors.
New US Licensing Pathways for Foreign-Trained Physicians
Learn how new state laws transform international medical graduate licensure in the United States and streamline career options.
Perioperative Enfortumab Vedotin-Pembrolizumab in MIBC
Phase 3 trial shows perioperative enfortumab vedotin-pembrolizumab improves event-free and overall survival in cisplatin-eligible bladder cancer patients.
Why Home Dialysis Fails to Reach Patients Who Need It Most
Explore the history of home dialysis barriers, political struggles, and socio-economic hurdles, with lessons for expanding dialysis access in India.
How to Master the New STROBE EPIC Reporting Standard
Discover how the new STROBE EPIC guideline changes reporting observational studies for incidence and prevalence, improving clinical research quality.